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Good news from Yahoo health

AIDS
BERLIN - An American man who suffered from AIDS appears to have been cured of the disease 20 months after receiving a targeted bone marrow transplant normally used to fight leukemia, his doctors said.

"German hematologists Eckhard Thiel and Gero Huetter of Berlin's Charite Medical University attend a news conference about a successful treatment of a HIV infected patient in Berlin, on Wednesday, Nov. 12, 2008."

While researchers — and the doctors themselves — caution that the case might be no more than a fluke, others say it may inspire a greater interest in gene therapy to fight the disease that claims 2 million lives each year. The virus has infected 33 million people worldwide.

Dr. Gero Huetter said Wedneday his 42-year-old patient, an American living in Berlin who was not identified, had been infected with the AIDS virus for more than a decade. But 20 months after undergoing a transplant of genetically selected bone marrow, he no longer shows signs of carrying the virus.

"We waited every day for a bad reading," Huetter said.

It has not come. Researchers at Berlin's Charite hospital and medical school say tests on his bone marrow, blood and other organ tissues have all been clean.

However, Dr. Andrew Badley, director of the HIV and immunology research lab at the Mayo Clinic in Rochester, Minn., said those tests have probably not been extensive enough.

"A lot more scrutiny from a lot of different biological samples would be required to say it's not present," Badley said.

This isn't the first time marrow transplants have been attempted for treating AIDS or HIV infection. In 1999, an article in the journal Medical Hypotheses reviewed the results of 32 attempts reported between 1982 and 1996. In two cases, HIV was apparently eradicated, the review reported.

Huetter's patient was under treatment at Charite for both AIDS and leukemia, which developed unrelated to HIV.

As Huetter — who is a hematologist, not an HIV specialist — prepared to treat the patient's leukemia with a bone marrow transplant, he recalled that some people carry a genetic mutation that seems to make them resistant to HIV infection. If the mutation, called Delta 32, is inherited from both parents, it prevents HIV from attaching itself to cells by blocking CCR5, a receptor that acts as a kind of gateway.

"I read it in 1996, coincidentally," Huetter told reporters at the medical school. "I remembered it and thought it might work."

Roughly one in 1,000 Europeans and Americans have inherited the mutation from both parents, and Huetter set out to find one such person among donors that matched the patient's marrow type. Out of a pool of 80 suitable donors, the 61st person tested carried the proper mutation.

Before the transplant, the patient endured powerful drugs and radiation to kill off his own infected bone marrow cells and disable his immune system — a treatment fatal to between 20 and 30 percent of recipients.

He was also taken off the potent drugs used to treat his AIDS. Huetter's team feared that the drugs might interfere with the new marrow cells' survival. They risked lowering his defenses in the hopes that the new, mutated cells would reject the virus on their own.

Anthony Fauci, director of the National Institute of Allergy and Infections Diseases in the U.S., said the procedure was too costly and too dangerous to employ as a firstline cure. But he said it could inspire researchers to pursue gene therapy as a means to block or suppress HIV.

"It helps prove the concept that if somehow you can block the expression of CCR5, maybe by gene therapy, you might be able to inhibit the ability of the virus to replicate," Fauci said.

David Roth, a professor of epidemiology and international public health at the London School of Hygiene and Tropical Medicine, said gene therapy as cheap and effective as current drug treatments is in very early stages of development.

"That's a long way down the line because there may be other negative things that go with that mutation that we don't know about."

Even for the patient in Berlin, the lack of a clear understanding of exactly why his AIDS has disappeared means his future is far from certain.

"The virus is wily," Huetter said. "There could always be a resurgence."
(This version CORRECTS spelling of doctor's name to Huetter throughout.)

Mr Leatherman Toronto Competition 2008

Canada's Premier Leather Event
Toronto, Canada. November 27 - 30, 2008

Once again Rainbow High Vacations and conxity.com are proud to be
the official travel partners for Mr Leatherman Toronto.
The gay and lesbian leather and fetish community
This event continues to garner good reviews from contestants and guests.
It attracts a great crowd from across North America.

Mr. Leatherman Toronto (MLT) hosts one of North America's largest leather gatherings, American Thanksgiving weekend. Four days of parties, meet-and-greets, dinners, brunches, a leather market and much more, climax at the Mr. Leatherman Toronto Competition 2009 and Victory Ball on Saturday November 29, 2008.

Fab Magazine calls the MLT weekend "one of the largest, wildest, and most euphoric leather celebrations anywhere in North America." Or, as Mr. Marcus of the Bay Area Reporter put it, MLT is "a spectacular show... One of the most butch-elegant amongst many high-quality productions.”

To help you plan to make the most of your MLT weekend, check out the list of events as well as conxGuide: Toronto which has lots of practical information about Canada's gay capital.

just click here for more info on joining this party.

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Gay Pride 2008 - Mexico D.F.

Marcha del Orgullo
"Ciudad de México"



Well over a million people come out in support of Mexico City Gay Pride,
which takes place over several days in late June (June 26 to June 30 in 2008).
Mexico's high-altitude capital city has a huge and active gay population,



although generally the gay scene is a bit more discreet and underground
than in other major North American metropolises.



The increasingly popular Mexico City Gay Pride,
however, is helping to heighten the LGBT community's visibility.

A good way to experience the Gay Pride festivities in Mexico City is to book
a Gay Pride tour through the reputable gay tour company, Arco Iris Tours.
If you're attending the Pride celebration on your own,



keep in mind that the Mexico City Gay Pride Parade takes place on June 28 at noon,
with the procession leading along Paseo de la Reforma and ending with a rally at Main Square (Zocalo).



Numerous gay clubs, hotels, pubs, and restaurants will also be holding events and offering special promotions during Mexico City's Gay Pride.

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watch on what they're doin there:

Hottest from Italia

Emanuele Fiore



This sexy guy was born in Torino-italia, i was enthralled by his cute face when he was 18, but he is dude now, with a big volume of muscle on his body. and his face also changes, more mature.

"but i feel western people, seems to be more quick in maturity. there's must be some explanation about it? why western man's getting quicker in maturity (biologically/anatomy) than asian man. is it becoz the food?... i saw a man when i was visiting bali for traveling and havin' fun there, may be australian, or european, he's tall (around 176 cm, could be) and da, his face seems to be like 18 years old for asian, but he's just around 15. well, nevermind"



he was invited to be a model of Esprit, and also to a
Italian underwear design [a famous Italian fashion house]
"Datch"

i thought it was Dutch. ha.... his body is really flatering, so stimulating.
he is hot there as we could see the pictures of him wearing the Datch underwear.

he has routinity of sit ups and
loving gym, he gives excercise to his muscle.

here is his brief bio:
born in Torino, italia, 1988
height 6'2" [187 cm]
suite size 38 [48]
waist 31 [78 cm]
collar 15 [37]
shoes 12 [43.5]
hair dark blonde eyes brown
he won the modeling contest
"L'umo Ideale d'Italia 06"
"An Ideal Italian Man 2006"

Here are his pictures, hope u like it:

Joe Jonas

Joseph Adam Jonas



This cute boy was born on August 15, 1989 in Casa Grande, Arizona, originally wanted to be a comedian. Then now, after knowing himself could singing, he is all about music. Joe is in a band called "the Jonas Brothers" and also known for his random sayings and sometimes crazy dances, he shares lead vocals with Nick Jonas, and sometimes plays the guitar and tambourine. he is with his two brothers Kevin and Nick in this group band. He has always loved music especially rock.



The Jonases are known for their wholesome, family-friendly image. The brothers are all committed Evangelical Christians, their father is a former pastor, and they were homeschooled by their mother. In addition, they all famously wear purity rings on their left-hand ring finger and have vowed not to have premarital sex.



Joe has said that the rings symbolize "a promise to ourselves and to God that we'll stay pure 'till marriage," and Nick had stated that "it's [purity rings] pretty awesome, and the rings are just one of our ways of kind of like being different than everybody else out there." They started wearing the rings when their parents, Denise and Kevin Sr., asked them if they wanted to. They also abstain from tobacco and drugs

Recognize if he is gay or not?

There is a highly accurate way a casual observer
can tell if a man is gay:
Just pay attention to his body type and the way he walks.

Both offer subtle cues about sexual orientation,
but casual observers seem to be able to read
those cues better in gay men than in lesbians,
according to a study from researchers at UCLA,
New York University and Texas A&M.

The study: Eight male and eight female volunteers,
half of whom were gay and half of whom were straight, participated.
Led by Kerri Johnson of UCLA, the team measured their hips, waists and shoulders.
Then each volunteer walked on a treadmill for
two minutes while being filmed by a 3D motion-capture system that
allowed researchers to track the precise
amount of shoulder swagger and hip sway in their gait.


The results: In terms of body motion or gait, gays and lesbians tended to have body types that were unusual for their gender. That is, gay men had hourglass figures, while the lesbians had more tubular bodies. In addition, the gay men tended to sway their hips, while the lesbian women swaggered their shoulders more than their straight counterparts.


The team then showed the treadmill videos--with only the volunteers' backsides visible--to 112 undergraduate observers. These students determined the volunteers' sexual orientation with an overall accuracy rate that exceeded chance, even though they could not see the volunteers' faces or the details of their clothing. Specifically, the students correctly categorized sexual orientation 60 percent of the time for men; however, their accuracy for women did not exceed what they would do just by chance.


"We already know that men and women are built differently and walk differently from each other and that casual observers use this information as clues in making a range of social judgments," Johnson said in a statement announcing the findings. "Now we've found that casual observers can use gait and body shape to judge whether a stranger is gay or straight with a small but perceptible amount of accuracy."

The findings build on recent research that shows that casual observers can often correctly identify sexual orientation with very limited information. A 1999 Harvard study, for example, found that just by looking at the photographs of seated strangers, college undergraduates were able to judge sexual orientation accurately 55 percent of the time.


"Studies like ours are raising questions about the value of the military's 'don't ask, don't tell' policy," Johnson said. "If casual observers can determine sexual orientation with minimal information, then the value in concealing this information certainly appears questionable. Given that we all appear to be able to deduce this information to some degree with just a glance, more comprehensive policies may be required to protect gays against discrimination based on their sexual orientation."

The study findings were published in the Journal of Personality and Social Psychology.